Inflammation and renal function decline in chronic coronary syndrome: a prospective multicenter cohort study.

ABSTRACT:

Background

Renal function decline is a frequently encountered complication in patients with chronic coronary syndrome. Aside from traditional cardiovascular risk factors, the inflammatory burden emerged as the novel phenotype that compromised renal prognosis in such population.

Methods

A cohort with chronic coronary syndrome was enrolled to investigate the association between inflammatory status and renal dysfunction. Levels of inflammatory markers, including high-sensitivity C-reactive protein (hs-CRP), tumour necrosis factor-α (TNF-α), adiponectin, matrix metalloproteinase-9, interleukin-6, lipoprotein-associated phospholipase A2, were assessed. Renal event was defined as > 25% decline in estimated glomerular filtration rate (eGFR). Inflammatory scores were calculated base

SUBMITTER: Kao TW 

PROVIDER: S-EPMC10655285 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature