Molecular characteristics of Neisseria meningitidis carriage strains in university students in Lithuania.

ABSTRACT:

Background

Neisseria meningitidis can be carried asymptomatically in the human oropharynx without causing symptoms. Meningococcal carriage is relevant to the epidemiology of invasive meningococcal disease (IMD). No carriage studies have been performed among the general population in Lithuania, whereas the incidence of IMD in Lithuania was among the highest in European countries from 2009 to 2019.

Results

We analyzed a total of 401 oropharyngeal samples collected from university students from December 2021 to February 2023 for N. meningitidis carriage using direct swab PCR assays and culture. The overall carriage prevalence based on both or either swab PCR or culture was 4.99%. PCR-based assays were used to characterize 15 carriage isolates, including detection of genogroup,

SUBMITTER: Ivaskeviciene I 

PROVIDER: S-EPMC10655475 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature