Effects of 2-year physical activity and dietary intervention on adrenarchal and pubertal development: the PANIC study.

ABSTRACT:

Context

Childhood overweight has been linked to earlier development of adrenarche and puberty, but it remains unknown if lifestyle interventions influence sexual maturation in general populations.

Objective

To investigate if a 2-year lifestyle intervention influences circulating androgen concentrations and sexual maturation in a general population of children.

Design and participants

A 2-year intervention study in which 421 prepubertal and mostly normal-weight 6-9-year-old children were allocated either to a lifestyle intervention group (119 girls, 132 boys) or a control group (84 girls, 86 boys).

Intervention

A 2-year physical activity and dietary intervention.

Main outcome measures

Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, androsten

SUBMITTER: Liimatta J 

PROVIDER: S-EPMC10655527 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature