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Improvement in severe asthma patients receiving biologics and factors associated with persistent insufficient control: a real-life national study.


ABSTRACT: Biological therapies have revolutionized the treatment of severe asthma with type 2 inflammation. Although such treatments are very effective in reducing exacerbation and the dose of oral steroids, little is known about the persistence of symptoms in severe asthma patients treated with biologics. We aim to describe asthma control and healthcare consumption of severe asthma patients treated with biologics. The Second Souffle study is a real-life prospective observational study endorsed by the Clinical Research Initiative in Severe Asthma: a Lever for Innovation & Science Network. Adults with a confirmed diagnosis of severe asthma for at least 12 months' duration were enrolled in the study. A self-administered questionnaire including the Asthma Control Questionnaire (ACQ), Asthma Quality of

SUBMITTER: Guilleminault L 

PROVIDER: S-EPMC10655663 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature