Effects of TNF-α inhibition versus secukinumab on active ultrasound-confirmed enthesitis in psoriatic arthritis.

ABSTRACT:

Introduction

Enthesitis is a hallmark of psoriatic disease, but its clinical assessment is problematic in terms of diagnostic sensitivity and overlap with other comorbid conditions. Ultrasound is a useful tool that can give a more detailed assessment of enthesitis. Research demonstrates that those with persistent ultrasound entheseal disease are at risk of progressive articular damage. With limited data to guide choice between biologic therapy for psoriatic arthritis (PsA) patients, we wanted to assess the response of ultrasound-confirmed enthesitis to different forms of biologic therapies and study its utility in making more informed decisions.

Methods

This was an open label observational study including patients aged ⩾18 years, who fulfil the classification criteria for PS

SUBMITTER: Elliott A 

PROVIDER: S-EPMC10655675 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature