Staged Surgically Created Type B Aortic Dissection Model with Endovascular Re-intervention for Different Morphological Features.

ABSTRACT:

Background

Understanding morphology and how this relates to treatment strategy is critical for achieving remodelling in aortic dissection. A controllable and reproducible large animal model is required for investigating new therapeutic devices and interventions.

Methods

Our experimental protocol involved the development of surgically created type B aortic dissection (SC-TBAD) and endovascular reintervention-induced TBAD (ERI-TBAD) porcine models. The sample was randomly divided into two groups: one underwent a secondary tear creation (STC) procedure, and the other underwent a false lumen extension (FLE) procedure. Anatomical features were observed at 1 and 3 months, and 2 animals in each group were euthanized at 3 months after the procedures. The aorta and main branches were

SUBMITTER: Guo B 

PROVIDER: S-EPMC10656095 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature