Evaluating the effects of brain injury, disease and tasks on cognitive fatigue.

ABSTRACT: Because cognitive fatigue (CF) is common and debilitating following brain injury or disease we investigated the relationships among CF, behavioral performance, and cerebral activation within and across populations by combining the data from two cross-sectional studies. Individuals with multiple sclerosis (MS) were included to model CF resulting from neurological disease; individuals who had sustained a traumatic brain injury (TBI) were included to model CF resulting from neurological insult; both groups were compared with a control group (Controls). CF was induced while neuroimaging data was acquired using two different tasks. CF significantly differed between the groups, with the clinical groups reporting more CF than Controls-a difference that was statistically significant for the TBI gr

SUBMITTER: Wylie GR 

PROVIDER: S-EPMC10656417 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature