Efficacy of bone defect therapy involving various surface treatments of titanium alloy implants: an in vivo and in vitro study.

ABSTRACT: Multiple surface treatment methods for titanium alloy prostheses, widely used in orthopedics, are available; however, these can affect bone integration and regeneration efficiency. In this study, through cell and animal experiments, we devised seven bone implant categories of Ti6Al4V based on surface preparation and post-processing technology (polishing, grit-blasting, fine titanium spraying, coarse titanium spraying, electron beam melting [EBM] printing, selective laser melting [SLM] printing, and post-processed SLM printing) and imaged each microscopic surface structure with a scanning electron microscope (SEM). Mechanical testing revealed excessive post-processing damaged the mechanical properties of the implants. In vitro, human bone marrow mesenchymal stem cells (hBMSCs) were cultured

SUBMITTER: Wang B 

PROVIDER: S-EPMC10656537 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature