Use of magnetic source imaging to assess recovery after severe traumatic brain injury-an MEG pilot study.

ABSTRACT:

Rationale

Severe TBI (sTBI) is a devastating neurological injury that comprises a significant global trauma burden. Early comprehensive neurocritical care and rehabilitation improve outcomes for such patients, although better diagnostic and prognostic tools are necessary to guide personalized treatment plans.

Methods

In this study, we explored the feasibility of conducting resting state magnetoencephalography (MEG) in a case series of sTBI patients acutely after injury (~7 days), and then about 1.5 and 8 months after injury. Synthetic aperture magnetometry (SAM) was utilized to localize source power in the canonical frequency bands of delta, theta, alpha, beta, and gamma, as well as DC-80 Hz.

Results

At the first scan, SAM source maps revealed zones of hypofunction, i

SUBMITTER: Sarma AK 

PROVIDER: S-EPMC10656620 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature