Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer.

ABSTRACT: Several studies have reported an association between the use of statins and breast cancer (BC) mortality. However, most of these studies did not take into account the underlying cholesterol level. To investigate the association between serum cholesterol, statin use, and BC mortality. This cohort study included females with invasive BC that was newly diagnosed between January 1, 1995, and December 31, 2013, in Finland. The cohort had available hormone receptor data and at least 1 cholesterol measurement. All data were obtained from Finnish national registries. Statistical analyses were performed from January to May 2022. Use of statins; statin dose; and serum cholesterol, low-density lipoprotein, high-density lipoprotein, and triglyceride levels measured separately before and after BC diagn

SUBMITTER: Murto MO 

PROVIDER: S-EPMC10656638 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature