Patient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer.

ABSTRACT:

Importance

Patient-reported outcomes (PROs), such as quality of life (QOL) and symptoms, are often associated with clinical outcomes in patients with cancer. In practice, oncologists use serum tumor markers (TMs) (ie, carcinoembryonic antigen [CEA] and carbohydrate antigen 19-9 [CA 19-9]) and imaging to monitor clinical outcomes in patients with gastrointestinal cancer.

Objective

To examine associations of 1-month changes in PROs and TMs with treatment response and survival among patients with gastrointestinal cancer.

Design, setting, and participants

This cohort study enrolled patients at Massachusetts General Hospital Cancer Center with at least 1 month follow-up from May 2019 to December 2020. Included patients were beginning first-line systemic therapy, aged 18 ye

SUBMITTER: Jarnagin JX 

PROVIDER: S-EPMC10656643 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature