Brain Volume in Fetal Alcohol Spectrum Disorders Over a 20-Year Span.

ABSTRACT:

Importance

Anomalous brain development and mental health problems are prevalent in fetal alcohol spectrum disorders (FASD), but there is a paucity of longitudinal brain imaging research into adulthood. This study presents long-term follow-up of brain volumetrics in a cohort of participants with FASD.

Objective

To test whether brain tissue declines faster with aging in individuals with FASD compared with control participants.

Design, setting, and participants

This cohort study used magnetic resonance imaging (MRI) data collected from individuals with FASD and control individuals (age 13-37 years at first magnetic resonance imaging [MRI1] acquired 1997-2000) compared with data collected 20 years later (MRI2; 2018-2021). Participants were recruited for MRI1 through the U

SUBMITTER: Pfefferbaum A 

PROVIDER: S-EPMC10656646 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature