Sequential host-bacteria and bacteria-bacteria interactions determine the microbiome establishment of Nematostella vectensis.

ABSTRACT:

Background

The microbiota of multicellular organisms undergoes considerable changes during host ontogeny but the general mechanisms that control community assembly and succession are poorly understood. Here, we use bacterial recolonization experiments in Nematostella vectensis as a model to understand general mechanisms determining bacterial establishment and succession. We compared the dynamic establishment of the microbiome on the germfree host and on inert silicone tubes.

Results

Following the dynamic reconstruction of microbial communities on both substrates, we show that the initial colonization events are strongly influenced by the host but not by the silicone tube, while the subsequent bacteria-bacteria interactions are the main driver of bacterial succession. Interes

SUBMITTER: Domin H 

PROVIDER: S-EPMC10656924 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature