Is There an Association Between Parkinson's Disease and Periodontitis? A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Multiple observational studies have yielded controversial results regarding the association between Parkinson's disease (PD) and periodontitis.

Objective

This systematic review and meta-analysis was conducted to ascertain their bidirectional relationship.

Methods

A literature search for relevant studies was performed in PubMed, EMBASE, the Cochrane Library, and Web of Science databases from inception to December 19, 2022. Effect sizes (ES) with 95% confidence intervals were pooled under the random-effects model. Then, leave-one-out sensitivity analysis and contour-enhanced funnel plot were applied to assess the stability of the results.

Results

A total of 34 studies and 24 studies were included for systematic review and quantitative meta-analysis, re

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10657691 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature