Effects of Brain Pathologies on Spatiotemporal Gait Parameters in Patients with Mild Cognitive Impairment.

ABSTRACT:

Background

Impaired gait can precede dementia. The associations between gait parameters and brain pathologies are therefore of interest.

Objective

To explore how different brain pathologies (i.e., vascular and Alzheimer's) are associated with specific gait parameters from various gait components in persons with mild cognitive impairment (MCI), who have an increased risk of developing dementia.

Methods

This cross-sectional study included 96 patients with MCI (mean 72, ±7.5 years; 52% women). Gait was evaluated by using an electronic walkway, GAITRite®. Four gait parameters (step velocity variability; step length; step time; stance time asymmetry) were used as dependent variables in multivariable linear regression analyses. Independent variables included Alzheimer's dis

SUBMITTER: Lindh-Rengifo M 

PROVIDER: S-EPMC10657715 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature