A Systematic Review on Retinal Biomarkers to Diagnose Dementia from OCT/OCTA Images.

ABSTRACT:

Background

Traditional methods for diagnosing dementia are costly, time-consuming, and somewhat invasive. Since the retina shares significant anatomical similarities with the brain, retinal abnormalities detected via optical coherence tomography (OCT) and OCT angiography (OCTA) have been studied as a potential non-invasive diagnostic tool for neurodegenerative disorders; however, the most effective retinal changes remain a mystery to be unraveled in this review.

Objective

This study aims to explore the relationship between retinal abnormalities in OCT/OCTA images and cognitive decline as well as evaluating biomarkers' effectiveness in detecting neurodegenerative diseases.

Methods

A systematic search was conducted on PubMed, Web of Science, and Scopus until December 20

SUBMITTER: Ibrahim Y 

PROVIDER: S-EPMC10657718 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature