Patterns of de novo metastasis and survival outcomes by age in breast cancer patients: a SEER population-based study.

ABSTRACT:

Background

The role of age in metastatic disease, including breast cancer, remains obscure. This study was conducted to determine the role of age in patients with de novo metastatic breast cancer.

Methods

Breast cancer patients diagnosed with distant metastases between 2010 and 2019 were retrieved from the Surveillance, Epidemiology, and End Results database. Comparisons were performed between young (aged ≤ 40 years), middle-aged (41-60 years), older (61-80 years), and the oldest old (> 80 years) patients. Adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) were estimated using multivariate Cox proportional hazard models. Survival analysis was performed by the Kaplan-Meier method.

Results

This study included 24155 (4.4% of all patients) de novo<

SUBMITTER: Xiao Q 

PROVIDER: S-EPMC10657995 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature