Photocatalytic effect of N-TiO₂ conjugated with folic acid against biofilm-forming resistant bacteria.

ABSTRACT: Antibiotic resistance challenges the treatment of bacterial biofilm-related infections, but the use of nanoparticles as a treatment is a promising strategy to overcome bacterial infections. This study applied nitrogen-doped titanium dioxide (N-TiO₂) conjugated with folic acid (FA) on biofilm-forming resistant bacteria. The photocatalytic effect of TiO₂ nanoparticles (NPs) was studied under ultraviolet (UV), visible light, and dark conditions at 60, 120, and 180 min against planktonic cells and biofilms of Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), and Pseudomonas aeruginosa. TiO₂ NPs were in the anatase phase, spherical shaped with sizes of 10-13 nm, and effectively doped and conjugated with N and FA. The

SUBMITTER: Oliveira RIS 

PROVIDER: S-EPMC10658382 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature