Simultaneous detection of neurotransmitters and Cu²⁺ using double-bore carbon fiber microelectrodes via fast-scan cyclic voltammetry.

ABSTRACT: There is a great demand to broaden our understanding of the multifactorial complex etiology of neurodegenerative diseases to aid the development of more efficient therapeutics and slow down the progression of neuronal cell death. The role of co-transmission and the effect of environmental factors on such diseases have yet to be explored adequately, mainly due to the lack of a proper analytical tool that can perform simultaneous multi-analyte detection in real time with excellent analytical parameters. In this study, we report a simple fabrication protocol of a double-bore carbon-fiber microelectrode (CFM) capable of performing rapid simultaneous detection of neurotransmitters and Cu²⁺via fast-scan cyclic voltammetry (FSCV) in Tris buffer. After imaging our CFMs via

SUBMITTER: Manring N 

PROVIDER: S-EPMC10658548 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature