Microbiome analysis of bile from apparently healthy cats and cats with suspected hepatobiliary disease.

ABSTRACT:

Background

Bacterial infection of bile is a common cause of hepatobiliary disease in cats. Whether bile harbors a core microbiota in health or in cases of suspected hepatobiliary disease in cats is unknown.

Objectives

Establish if gallbladder bile in apparently healthy cats harbors a core microbiota composed of bacterial taxa common to many individuals. Compare results of bile cytology, bile culture, and 16S rRNA gene amplicon sequencing in apparently healthy cats and cats with suspected hepatobiliary disease.

Animals

Forty-three client-owned cats with suspected hepatobiliary disease and 17 control cats.

Methods

Bile was collected by ultrasound guided cholecystocentesis (cats with suspected hepatobiliary disease) or laparotomy after euthanasia (controls). Bile

SUBMITTER: Slead TS 

PROVIDER: S-EPMC10658561 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature