Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging.

ABSTRACT: Photoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been challenging to demonstrate. In this study, we investigated the acoustic transmission through the human skull to design an ultrasound sensor suitable for transcranial PA imaging and sensing. We measured the frequency dependent losses of human cranial bones ex vivo, compared the performance of a range of piezoelectric and optical ultrasound sensors, and imaged skull phantoms using a PA tomograph based on a planar Fabry-Perot sensor. All transcranial photoacoustic measurements show the typical effects of frequency and thickness dependent attenuation and aberra

SUBMITTER: Kirchner T 

PROVIDER: S-EPMC10658602 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature