Burden and trajectory of multimorbidity in rheumatoid arthritis: a matched cohort study from 2006 to 2015.

ABSTRACT:

Objectives

To compare the onset and trajectory of multimorbidity between individuals with and without rheumatoid arthritis (RA).

Methods

A matched, retrospective cohort study was completed in a large, US commercial insurance database (MarketScan) from 2006 to 2015. Using validated algorithms, patients with RA (overall and incident) were age-matched and sex-matched to patients without RA. Diagnostic codes for 44 preidentified chronic conditions were selected to determine the presence (≥2 conditions) and burden (count) of multimorbidity. Cross-sectional comparisons were completed using the overall RA cohort and conditional logistic and negative binomial regression models. Trajectories of multimorbidity were assessed within the incident RA subcohort using generalised estimating

SUBMITTER: England BR 

PROVIDER: S-EPMC10658760 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature