Advancements in cell-based therapies for the treatment of pressure injuries: A systematic review of interventional studies.

ABSTRACT: The high recurrence and complications associated with severe pressure injuries (PI) necessitate the exploration of advanced treatments, such as cell-based therapies, to facilitate wound healing. Such techniques harness the ability of different cell types to promote angiogenesis, re-epithelialization of the skin, and tissue regeneration. This systematic review explores the efficacy of cell-based therapies and tissue engineering in treating deep PI. We searched for interventional studies using cells in the treatment of PI in adults in four online libraries (PubMed, Embase, Ovid Medline, and Cochrane; latest search 10th June 2023). We found one randomized clinical trial (RCT), two non-RCT, and three pre-post studies, comprising 481 study participants with PI (253 intervention/228 controls). T

SUBMITTER: Camesi A 

PROVIDER: S-EPMC10658773 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature