Risk prediction model for mortality in microscopic polyangiitis: multicentre REVEAL cohort study.

ABSTRACT:

Background

To establish refined risk prediction models for mortality in patients with microscopic polyangiitis (MPA) by using comprehensive clinical characteristics.

Methods

Data from the multicentre Japanese registry of patients with vasculitis (REVEAL cohort) were used in our analysis. In total, 194 patients with newly diagnosed MPA were included, and baseline demographic, clinical, laboratory, and treatment details were collected. Univariate and multivariate analyses were conducted to identify the significant risk factors predictive of mortality.

Results

Over a median follow-up of 202.5 (84-352) weeks, 60 (30.9%) of 194 patients died. The causes of death included MPA-related vasculitis (18.3%), infection (50.0%), and others (31.7%). Deceased patients were older (me

SUBMITTER: Kotani T 

PROVIDER: S-EPMC10658814 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature