Genome-wide expression QTL mapping reveals the highly dynamic regulatory landscape of a major wheat pathogen.

ABSTRACT:

Background

In agricultural ecosystems, outbreaks of diseases are frequent and pose a significant threat to food security. A successful pathogen undergoes a complex and well-timed sequence of regulatory changes to avoid detection by the host immune system; hence, well-tuned gene regulation is essential for survival. However, the extent to which the regulatory polymorphisms in a pathogen population provide an adaptive advantage is poorly understood.

Results

We used Zymoseptoria tritici, one of the most important pathogens of wheat, to generate a genome-wide map of regulatory polymorphism governing gene expression. We investigated genome-wide transcription levels of 146 strains grown under nutrient starvation and performed expression quantitative trait loci (eQTL) mapping. We i

SUBMITTER: Abraham LN 

PROVIDER: S-EPMC10658818 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature