Ventricular dyssynchrony late after the Fontan operation is associated with decreased survival.

ABSTRACT:

Background

Ventricular dyssynchrony and its relationship to clinical outcomes is not well characterized in patients following Fontan palliation.

Methods

Single-center retrospective analysis of cardiac magnetic resonance (CMR) imaging of patients with a Fontan circulation and an age-matched healthy comparison cohort as controls. Feature tracking was performed on all slices of a ventricular short-axis cine stack. Circumferential and radial strain, strain rate, and displacement were measured; and multiple dyssynchrony metrics were calculated based on timing of these measurements (including standard deviation of time-to-peak, maximum opposing wall delay, and maximum base-to-apex delay). Primary endpoint was a composite measure including time to death, heart transplant or heart t

SUBMITTER: Gearhart A 

PROVIDER: S-EPMC10658858 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature