Avian Sex Determination: A Chicken and Egg Conundrum.

ABSTRACT:

Background

Primary sex determination is the developmental process that results in the sexual differentiation of the gonads. Vertebrate sex determination is generally considered to follow the model based on the mammalian system, where a sex-specific master regulatory gene activates one of the two different gene networks that underlie testis and ovary differentiation.

Summary

It is now known that, while many of the molecular components of these pathways are conserved across different vertebrates, a wide variety of different trigger factors are utilized to initiate primary sex determination. In birds, the male is the homogametic sex (ZZ), and significant differences exist between the avian system of sex determination and that of mammals. For example, DMRT1, FOXL2, and estrogen

SUBMITTER: Clinton M 

PROVIDER: S-EPMC10659007 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature