Associations between D₃Cr muscle mass and MR thigh muscle volume with strength, power, physical performance, fitness, and limitations in older adults in the SOMMA study.

ABSTRACT:

Background

Different measures to assess muscle size - magnetic resonance (MR) derived thigh muscle volume and d3-creatine dilution derived muscle mass (D₃Cr muscle mass) - may have similar associations with strength, power, physical performance, fitness, and functional limitations in older adults.

Methods

Men (N=345) and women (N=482) aged ≥70 years from the Study of Muscle, Mobility and Aging completed exams including leg extension strength (1-repetition max) and cardiopulmonary exercise testing to assess fitness (VO₂peak). Correlations and adjusted regression models stratified by sex were used to assess the association between muscle size measures and study outcomes; we tested for sex interactions.

Results

D₃Cr muscle mass and MR thi

SUBMITTER: Cawthon PM 

PROVIDER: S-EPMC10659521 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature