Prognostic evaluation of stage I lung adenocarcinoma based on systematic inflammatory response.

ABSTRACT:

Background

This study aimed to construct an effective nomogram based on the clinical and laboratory characteristics to predict the prognosis of stage I lung adenocarcinoma with EGFR alteration.

Methods

A retrospective study was performed of 913 eligible patients with EGFR alteration after surgery at Shanghai Pulmonary Hospital. The peripheral blood indicators were included in the nomogram. Calibration plots, concordance index, decision curve analysis, and X-tile software were used in this study. Recurrence-free survival (RFS) and overall survival were estimated by the Kaplan-Meier method and compared using the log-rank test.

Results

Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio were independent risk factors for RFS. The calibration curves for RFS pro

SUBMITTER: Qian JY 

PROVIDER: S-EPMC10660118 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature