Evaluation of Predict, a prognostic risk tool, after diagnosis of a second breast cancer.

ABSTRACT:

Background

The UK National Health Service's Predict is a clinical tool widely used to estimate the prognosis of early-stage breast cancer. The performance of Predict for a second primary breast cancer is unknown.

Methods

Women 18 years of age or older diagnosed with a first or second invasive breast cancer between 2000 and 2013 and followed for at least 5 years were identified from the US Surveillance, Epidemiology, and End Results (SEER) database. Model calibration of Predict was evaluated by comparing predicted and observed 5-year breast cancer-specific mortality separately by estrogen receptor status for first vs second breast cancer. Receiver operating characteristic curves and areas under the curve were used to assess model discrimination. Model performance was also eva

SUBMITTER: Deng Z 

PROVIDER: S-EPMC10660126 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature