Tight perioperative blood pressure management to reduce complications: a randomised feasibility trial.

ABSTRACT:

Objective

Evaluate the feasibility of a trial of perioperative hypotension and serious complications.

Design

A patient and assessor-blinded randomised feasibility trial.

Setting

We included patients in a tertiary university hospital.

Participants

We enrolled 80 adults scheduled for major non-cardiac surgery.

Interventions

In patients randomised to tight blood pressure control, intraoperative mean arterial pressure (MAP) was targeted to ≥85 mm Hg maintained with norepinephrine infusion, and restarting chronic antihypertensive medications was delayed until the third postoperative day. In the reference group, intraoperative blood pressure was managed per routine and antihypertensive medications were restarted immediately after surgery.

Primary and second

SUBMITTER: Li K 

PROVIDER: S-EPMC10660199 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature