Indices of sarcopenic obesity are important predictors of finite element analysis-derived bone strength in older adults with obesity.

ABSTRACT:

Background

The expanding population of older adults with obesity is a public health challenge, in part, because of the increased risk of fractures despite normal or high bone mineral density. Potential factors predisposing to fractures in this group include sarcopenia associated with obesity and impaired bone quality. We aimed to determine the contribution of sarcopenic obesity (SO) indices to bone strength as assessed by microfinite element analysis (μFEA) of high-resolution peripheral quantitative computed tomography (HR-pQCT).

Methods

One-hundred eighty-nine older (age ≥ 65 years) adults with obesity (BMI ≥ 30 kg/m²) participated in lifestyle intervention trials at our medical center. All underwent baseline measurements of bone strength (failure load and stiffn

SUBMITTER: Gregori G 

PROVIDER: S-EPMC10660264 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature