Unveiling invisible farm-to-farm PRRSV-2 transmission links and routes through transmission tree and network analysis.

ABSTRACT: The United States (U.S.) swine industry has struggled to control porcine reproductive and respiratory syndrome (PRRS) for decades, yet the causative virus, PRRSV-2, continues to circulate and rapidly diverges into new variants. In the swine industry, the farm is typically the epidemiological unit for monitoring, prevention, and control; breaking transmission among farms is a critical step in containing disease spread. Despite this, our understanding of farm transmission still is inadequate, precluding the development of tailored control strategies. Therefore, our objective was to infer farm-to-farm transmission links, estimate farm-level transmissibility as defined by reproduction numbers (R), and identify associated risk factors for transmission using PRRSV-2 open reading frame 5 (

SUBMITTER: Pamornchainavakul N 

PROVIDER: S-EPMC10660809 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature