Molecular Docking and ADME-TOX Profiling of Moringa oleifera Constituents against SARS-CoV-2.

ABSTRACT: The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2019) etiological agent, which has a high contagiousness and is to blame for the outbreak of acute viral pneumonia, is the cause of the respiratory disease COVID-19. The use of natural products grew as an alternative treatment for various diseases due to the abundance of organic molecules with pharmacological properties. Many pharmaceutical studies have focused on investigating compounds with therapeutic potential. Therefore, this study aimed to identify potential antiviral compounds from a popular medicinal plant called Moringa oleifera Lam. against the spike, M^pro, ACE2, and RBD targets of SARS-CoV-2. For this, we use molecular docking to identify the molecules with the greatest affinity for the targets throu

SUBMITTER: Souza HCA 

PROVIDER: S-EPMC10660866 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature