Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The study aimed to review differences in the presentation and outcomes of acute pulmonary embolism (PE) between men and women.

Methods

PubMed, CENTRAL, Web of Science, and Embase were searched for studies comparing clinical features or outcomes of PE between men and women. Baseline comorbidities, risk factors, clinical features, and mortality rates were also compared between men and women.

Results

Fourteen studies were included. It was noted that men presented with PE at a statistically significantly younger age than women (P < .001). Smoking history (P < .001), lung disease (P = .004), malignancy (P = .02), and unprovoked PE (P = .004) were significantly more frequent among men than among women. There was no difference between the sexes for hypertension, d

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10660947 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature