Multi-function screening of probiotics to improve oral health and evaluating their efficacy in a rat periodontitis model.

ABSTRACT: The oral cavity is the second most microbially rich region of the human body, and many studies have shown that there is a strong association between microorganisms and oral health. Some pathogenic bacteria produce biofilms and harmful metabolites in the mouth that may cause oral problems such as oral malodor, periodontitis, and dental caries. Altering the oral microbiota by using probiotics may alleviate oral health problems. Thus, using multi-function screening, we aimed to identify probiotics that can significantly improve oral health. The main parameters were the inhibition of pathogenic bacteria growth, inhibition of biofilm formation, reduction in the production of indole, H₂S, and NH₃ metabolites that cause halitosis, increase in the production of H₂O

SUBMITTER: Nie Q 

PROVIDER: S-EPMC10660970 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature