Sinus node dysfunction and stroke risk: a systematic review and meta-analysis.

ABSTRACT:

Objectives

The role of cardiac arrhythmia in ischaemic stroke is widely studied, but the size of the stroke risk in patients with sinus node dysfunction (SND) with and without atrial fibrillation (AF) is unclear. This systematic review and meta-analysis aimed to compare the risk of stroke and its associated factors in patients with SND with and without AF.

Design

A systematic review and meta-analysis was conducted based on the Grading of Recommendations, Assessment, Development and Evaluation approach.

Data sources

PubMed, EMBASE and Cochrane Database were searched until December 2022.

Eligibility criteria for selecting studies

Studies that investigate stroke in patients with SND diagnosed with or without AF/atrial flutter.

Data extraction and synthesis

SUBMITTER: Dong H 

PROVIDER: S-EPMC10660976 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature