Is Lymphadenectomy Reasonable for Elderly Intrahepatic Cholangiocarcinoma Patients?

ABSTRACT:

Background

In this study, we aimed to determine the impact of lymphadenectomy (LND) on clinical outcomes in ICC patients aged ≥ 70 years.

Methods

Four hundred and three eligible patients diagnosed with ICC who underwent hepatectomy between 2004 and 2019 were enrolled in the Surveillance, Epidemiology, and End Results database. The impact of LND on perioperative mortality and overall survival (OS) as well as the optimal total number of lymph nodes examined (TNLE) was estimated.

Results

One hundred thirty-nine pairs of patients were matched by propensity score matching. Perioperative mortality was comparable between the LND and non-LND (nLND) groups (0.7% vs. 2.9%, P = 0.367). The median OS in the LND group was significantly longer (44 vs. 32 months, P = 0.045) and LND

SUBMITTER: Lin Q 

PROVIDER: S-EPMC10661814 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature