Association between Statins Types with Incidence of Liver Cancer: An Updated Meta-analysis.

ABSTRACT:

Background

Previous studies have found a potential role for statins in liver cancer prevention.

Objective

This study aimed to explore the effect of different types of statins on the incidence of liver cancer.

Methods

Relevant articles were systematically retrieved from PubMed, EBSCO, Web of Science, and Cochrane Library databases from inception until July 2022 to explore the relationship between lipophilic statins or hydrophilic statins exposure and the incidence of liver cancer. The main outcome was the incidence of liver cancer.

Results

Eleven articles were included in this meta-analysis. The pooled results showed a reduced incidence of liver cancer in patients exposed to lipophilic statins (OR=0.54, p < 0.001) and hydrophilic statins (OR=0.56, p < 0.001)

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10661961 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature