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ABSTRACT: Background
This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians an overview of type 2 diabetes mellitus (T2DM), an obesity-related cardiometabolic risk factor.Methods
The scientific support for this CPS is based upon published citations and clinical perspectives of OMA authors.Results
Topics include T2DM and obesity as cardiometabolic risk factors, definitions of obesity and adiposopathy, and mechanisms for how obesity causes insulin resistance and beta cell dysfunction. Adipose tissue is an active immune and endocrine organ, whose adiposopathic obesity-mediated dysfunction contributes to metabolic abnormalities often encountered in clinical practice, including hyperglycemia (e.g., pre-diabetes mellitus and T2DM
SUBMITTER: Bays HE
PROVIDER: S-EPMC10661981 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature