Impact of sex differences on cardiac injury in critically ill patients with COVID-19.

ABSTRACT:

Background

COVID-19 infections are associated with accrued inflammatory responses which may result in cardiac injury. Immune response to infection appears different between men and women, suggesting that COVID-19 patients' outcomes may differ according to biological sex. However, the impact of biological sex on the occurrence of cardiac injury during intensive care unit (ICU) stay in COVID-19 patients remain unclear.

Methods

In this multicenter and prospective study, we included consecutive patients admitted to ICU for severe COVID-19 pneumonia, during the first two pandemic waves. Biological, electrocardiogram (ECG) and echocardiographic variables were collected on ICU admission. Cardiac injury was defined by increased troponin above 99th percentile of upper norm value and

SUBMITTER: Jozwiak M 

PROVIDER: S-EPMC10662091 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature