Cumulative environmental quality is associated with breast cancer incidence differentially by summary stage and urbanicity.

ABSTRACT: Individual environmental contaminants have been associated with breast cancer; however, evaluations of multiple exposures simultaneously are limited. Herein, we evaluated associations between breast cancer summary stages and the Environmental Quality Index (EQI), which includes a range of environmental factors across five domains. The EQI (2000-2005) was linked to county-level age-standardized incidence rates (SIRs) obtained from the North Carolina Central Cancer Registry (2010-2014). Incidence rates and SIRs of total, in situ, localized, regional, and distant breast cancers were evaluated stratified by rural-urban status. In counties with poor environmental quality compared to those with good environmental quality, total breast cancer incidence was higher by 10.82 cases per 100,000 person

SUBMITTER: Gearhart-Serna LM 

PROVIDER: S-EPMC10662118 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature