Establishing the link between microbial communities in bovine liver abscesses and the gastrointestinal tract.

ABSTRACT:

Background

Liver abscesses (LAs) are one of the most common and important problems faced by the beef industry. The most efficacious method for the prevention of LAs in North America is through dietary inclusion of low doses of antimicrobial drugs such as tylosin, but the mechanisms by which this treatment prevents LAs are not fully understood. LAs are believed to result from mucosal barrier dysfunction in the gastrointestinal tract (GIT) allowing bacterial translocation to the liver via the portal vein, yet differences in the GIT microbiome of cattle with and without LAs have not been explored. Here, we characterized microbial communities from LAs, rumen, ileum, and colon from the same cattle for the first time.

Results

Results demonstrate that tylosin supplementation was as

SUBMITTER: Pinnell LJ 

PROVIDER: S-EPMC10662489 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature