Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain.

ABSTRACT:

Study design

Secondary analyses of a randomized trial [Antibiotics In Modic changes (MCs) study].

Objective

To assess whether or not reduced MC edema over time is related to reduced disability and pain in patients with chronic low back pain (LBP).

Summary of background data

It is not clear whether or not reduced MC edema implies improved clinical outcomes.

Patients and methods

Linear regression was conducted separately in 2 subgroups with MC edema at baseline on short tau inversion recovery (STIR) or T1/T2-weighted magnetic resonance imaging, respectively. Independent variable: reduced edema (yes/no) at 1 year on STIR or T1/T2-series, respectively. Dependent variable: 1-year score on the Roland-Morris Disability Questionnaire (RMDQ), Oswestry Disability Index (

SUBMITTER: Espeland A 

PROVIDER: S-EPMC10662590 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature