Rifampin Mono-Resistant Tuberculosis in New York City, 2010-2021: A Retrospective Case Series.

ABSTRACT:

Background

Although relatively rare, rifampin mono-resistant tuberculosis (RMR TB) poses important challenges to effective TB treatment and control. Information on the burden of RMR TB and treatment outcomes is needed to inform diagnosis and management.

Methods

Standardized variables were collected from the New York City (NYC) tuberculosis surveillance system for patients treated for RMR TB in NYC during 2010-2021.

Results

Of 7097 TB cases reported in 2010-2021, 31 (<1%) were treated clinically as RMR TB. Five (16%) of these patients had HIV. Seventeen patients (55%) had TB that was rifampin-resistant by both molecular and phenotypic drug susceptibility testing; 2 (6%) had rifampin resistance by phenotypic tests, and molecular tests were not done; and 12 (39%) were id

SUBMITTER: Lindsey JA 

PROVIDER: S-EPMC10662657 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature