Transcranial direct current stimulation in semantic variant of primary progressive aphasia: a state-of-the-art review.

ABSTRACT: The semantic variant of primary progressive aphasia (svPPA), known also as "semantic dementia (SD)," is a neurodegenerative disorder that pertains to the frontotemporal lobar degeneration clinical syndromes. There is currently no approved pharmacological therapy for all frontotemporal dementia variants. Transcranial direct current stimulation (tDCS) is a promising non-invasive brain stimulation technique capable of modulating cortical excitability through a sub-threshold shift in neuronal resting potential. This technique has previously been applied as adjunct treatment in Alzheimer's disease, while data for frontotemporal dementia are controversial. In this scoped review, we summarize and critically appraise the currently available evidence regarding the use of tDCS for improving performa

SUBMITTER: Norata D 

PROVIDER: S-EPMC10663282 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature