Leveraging African American family connectors for Alzheimer's disease genomic studies.

ABSTRACT:

Introduction

The underrepresentation of African Americans (AAs) in Alzheimer's disease (AD) research may limit potential benefits from translational applications. This article describes an approach to recruit AA families into an AD genomic study and characteristics of seeds (family connectors) used to overcome recruitment barriers of AA families into AD research.

Methods

A four-step outreach and snowball sampling approach relying on family connectors was used to recruit AA families. Descriptive statistics of a profile survey were gathered to understand the demographic and health characteristics of family connectors.

Results

Twenty-five AA families (117 participants) were enrolled in the study via family connectors. Most family connectors self-identified as female (88%

SUBMITTER: Byfield G 

PROVIDER: S-EPMC10663385 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature