Comparative effectiveness of new treatment modalities for localized prostate cancer through patient-reported outcome measures.

ABSTRACT:

Purpose

There is scarce comparative effectiveness research on the new treatment modalities for localized prostate cancer. We aim to compare through Patient-Reported Outcome Measures (PROMs) the impact of active surveillance, robot-assisted radical prostatectomy (RARP), intensity-modulated radiotherapy (IMRT), and real-time brachytherapy, considering side effects (incontinence, irritative/obstructive urinary symptoms, sexual dysfunction and bowel symptoms) and physical and mental health.

Materials and methods

Prospective cohort of men diagnosed with clinically localized prostate cancer (age 50-75y, T1-T2, and low risk including Gleason 3 + 4 in T1c) from 18 Spanish hospitals, followed up to 24 months. Treatment decisions were jointly made by patients and physicians (n = 572).

SUBMITTER: Zamora V 

PROVIDER: S-EPMC10663757 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature