CoreDetector: a flexible and efficient program for core-genome alignment of evolutionary diverse genomes.

ABSTRACT:

Motivation

Whole genome alignment of eukaryote species remains an important method for the determination of sequence and structural variations and can also be used to ascertain the representative non-redundant core-genome sequence of a population. Many whole genome alignment tools were first developed for the more mature analysis of prokaryote species with few current tools containing the functionality to process larger genomes of eukaryotes as well as genomes of more divergent species. In addition, the functionality of these tools becomes computationally prohibitive due to the significant compute resources needed to handle larger genomes.

Results

In this research, we present CoreDetector, an easy-to-use general-purpose program that can align the core-genome sequences for a

SUBMITTER: Fruzangohar M 

PROVIDER: S-EPMC10663985 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature