Tooth-level predictors of tooth loss and exposed bone after radiation therapy for head and neck cancer.

ABSTRACT:

Background

The objective of this study was to identify tooth-level risk factors for use during preradiation dental care management to predict risk of tooth failure (tooth lost or declared hopeless) and exposed bone after radiation therapy (RT) for head and neck cancer (HNC).

Methods

The authors conducted a prospective observational multicenter cohort study of 572 patients receiving RT for HNC. Participants were examined by calibrated examiners before RT and then every 6 months until 2 years after RT. Analyses considered time to tooth failure and chance of exposed bone at a tooth location.

Results

The following pre-RT characteristics predicted tooth failure within 2 years after RT: hopeless teeth not extracted pre-RT (hazard ratio [HR], 17.1; P < .0001), untreated cari

SUBMITTER: Lalla RV 

PROVIDER: S-EPMC10664022 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature